Dahe Network News (Reporter Zhu Chuanpeng) In recent years, the incidence of diabetes has increased year by year. Epidemiological survey data show that the prevalence of diabetes in my country is 12.8%, and the number of patients has exceeded 140 million. Among them, as many as 35.2% are pre-diabetic patients, which is a very large number of patients.
As a populous province, Henan has 7 million patients with diabetes, and as many as 13 million people with pre-diabetes. Diabetes is a major public health problem in my country. , the prevention and control situation is grim, and effective therapeutic drugs that can achieve full intervention in diabetes are urgently needed.
Diabetes is extremely harmful to health and can lead to various complications such as heart, brain, kidney, nerve, and blood vessels. If Is it just abnormal glucose tolerance at this stage? What are the dangers of impaired glucose tolerance? How to treat? During the “Tongxin Tongluo Healthy China Tour” – the 2024 Central Plains Collateral Disease Academic Conference, relevant experts answered this hot issue.
What is impaired glucose tolerance? What’s the harm?
“Abnormal glucose tolerance is a gap between normal people and diabetes.An abnormal state of glucose metabolism. “Professor Shi Suqin from the First Affiliated Hospital of Henan University of Chinese Medicine introduced that in short, abnormal glucose tolerance means that during a glucose tolerance test, the patient’s fasting blood glucose is less than 7 mmol per liter, but the blood glucose two hours after oral administration of sugar water is 7.8 Between 11.1 mmol per liter and 11.1 millimoles per liter, this is higher than normal blood sugar but does not meet the diagnostic criteria for diabetes. This situation is called abnormal glucose tolerance.
“Abnormal glucose tolerance has an impact on both cardiovascular disease and microvascular complications. “When talking about the dangers of abnormal glucose tolerance, Professor Zhang Dongming from the Second Affiliated Hospital of Zhengzhou University said this.
According to him, some studies have found , the risk of cardiovascular and cerebrovascular diseases in patients with abnormal glucose tolerance is significantly increased. In addition, some studies have also found that patients with abnormal glucose tolerance are also at a higher risk of developing microvascular complications, such as diabetic peripheral neuropathy, diabetic retinopathy, and diabetic nephropathy. High in other groups
How to treat abnormal glucose tolerance?
How to deal with abnormal glucose tolerance? Can drug treatment effectively control it? In this regard, Professor Zheng Lili from the First Affiliated Hospital of Zhengzhou University said that currently, the main treatment for abnormal glucose tolerance is daily life. Modal intervention. If lifestyle intervention is ineffective for 6 months, drug intervention is usually required, such as metformin, pioglitazone, acarbose, semaglutide and other drugs. However, when using Western drugs, some patients will suffer from side effects of the drugs. Difficulty adhering to treatment
In the field of diabetes treatment, “JAMA Internal Medicine” not long ago. ) published the “Preventive Effect of Jinlida on Diabetes in People with Abnormal Glucose Tolerance Combined with Multiple Metabolic Disorders—FOCUS Randomized Clinical Trial”. The research results show that Jinlida can significantly reduce the risk of diabetes in people with abnormal glucose tolerance41 %.
How can such research results be helpful to clinical practice? Professor Zheng Lili said that this research is aimed at the early stage of chronic metabolic diseases in my country. The difficulty of intervention and treatment, that is, the intervention and treatment of people with abnormal glucose tolerance and multiple metabolic disorders who develop diabetes. This is the first time that my country has released a Chinese patent medicine to the world as a substitute.Xie Syndrome’s “Are you angry that Brother Sehun hasn’t contacted you these days? There is a reason, because I have been trying to convince my parents to take back my life and tell them that we really love each other.
Professor Shi Suqin said that the FOCUS study showed that long-term oral administration of Jinlida can reduce the risk of developing diabetes in high-risk groups. The group had significant improvements in key indicators such as waist circumference, body mass index, fasting blood glucose, 2-hour postprandial blood glucose, and glycosylated hemoglobin.
“Treating diabetes is primarily about preventing complications. “Professor Zheng Lili said that the FOCUS study showed that Jinlida may also have a positive impact on patients’ cardiovascular health, which is reflected in the ankle-brachial index (ABI) and carotid intima-media thickness (CIMT) of the Jinlida group after treatment. There is a significant improvement. The improvement of these indicators may indicate a reduction in the risk of cardiovascular events. Professor Zheng Lili said, “The FOCUS study provides clinical benefits. Doctors have brought a more effective tool. On the basis of lifestyle intervention, when giving patients drug intervention, the addition of Jinlida can achieve good curative effects. This is its significance. ”
“The FOCUS study is an important event in the field of traditional Chinese medicine to explore the prevention of diabetes, and it is an epoch-making event. “Professor Zhang Dongming said that in recent years, the development of evidence-based research on traditional Chinese medicine has made great progress. Jinlida FOCUS research has further pushed traditional Chinese medicine research into modernization and internationalization, and has also set an example for traditional Chinese medicine research.
She was not in a hurry to ask anything. She asked her son to sit down first, and then poured him a glass of water for him to drink. Seeing him shaking his head vigorously to make himself more awake, she spoke.